New clues reveal how gestational diabetes affects offspring

Researchers have discovered a new mechanism linking gestational diabetes to pregnancy complications. The study found that gestational diabetes alters the placenta’s processing of genetic messages, leading to incorrect assembly of hundreds of genetic messages and potentially disrupting placental function. The researchers identified a key protein, SRSF10, that appears to contribute to this disrupted process. Targeting SRSF10 may help mitigate the effects of gestational diabetes on offspring. The study’s findings provide new insights into the underlying biology of gestational diabetes and open up new avenues for intervention to improve pregnancy outcomes.

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