A groundbreaking study has found that reversing prediabetes through lifestyle changes can cut the risk of heart attack, heart failure, and premature death by 50%. Researchers analyzed data from over 2,400 people with prediabetes and found that those who normalized their blood glucose levels had a significantly lower risk of cardiovascular disease. A fasting blood glucose value of ≤ 97 mg/dL is a simple marker for lower heart disease risk. The study’s findings suggest that sustained normalization of blood glucose should be a key target for clinical guidelines, adding a fourth pillar to cardiovascular prevention.